Review
Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)
1 Department of Surgery, Macerata Hospital, Macerata, Italy
2 Emergency Surgery, Maggiore Parma Hospital, Parma, Italy
3 Department of General Surgery, Ospedali Riuniti, Bergamo, Italy
4 Department of Surgery, Denver Health Medical Center, Denver, CO, USA
5 American Board of Surgery, Philadelphia, PA, USA
6 Harvard Medical School, Division of Trauma, Emergency Surgery and Surgical Critical Care Massachusetts General Hospital, Boston, MA, USA
7 Department of Surgery, UC San Diego Health System, San Diego, CA, USA
8 Department of Primary Care & Emergency Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
9 Department of Abdominal Surgery, University Hospital Meilahti, Helsinki, Finland
10 Department of Surgery, University of Newcastle, Newcastle, NSW, Australia
11 Department of Surgery, Govt Medical College and Hospital, Chandigarh, India
12 Department of General Surgery, Rambam Health Care Campus, Haifa, Israel
13 Department of Surgery, Adria Hospital, Adria, Italy
14 Trauma Surgery Unit, Maggiore Hospital, Bologna, Italy
15 Department of Surgery, Maggiore Hospital, Bologna, Italy
16 Department of Surgery, Universidad del Valle, Fundacion Valle del Lili, Cali, Colombia
17 Department of Surgery, Monte Sinai Hospital, Juiz de Fora, Brazil
18 Emergency Unit, Department of Surgery, Ribeirão Preto, Brazil
19 Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan
20 Department of General Surgery, Hadassah Medical Center, Jerusalem, Israel
21 Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, Tianjin, China
22 Department of Surgery, Pt BDS Post-graduate Institute of Medical Sciences, Rohtak, India
23 Department of Surgery, MOSC medical college, Cochin, India
24 First Clinic of General Surgery, University Hospital /UMBAL/ St George Plovdiv, Plovdiv, Bulgaria
25 General Surgery Clinic, Medical University/University Hospital St.George, Plovdiv, Bulgaria
26 Department of Surgery, Edendale Hospital, Pietermaritzburg, Republic of South Africa
27 Department of Surgery, Ahmadu Bello University Teaching Hospital Zaria, Kaduna, Nigeria
28 Department of Surgery, Mansoura University Hospital, Mansoura, Egypt
29 Department of Surgery, Faculdades Integradas Padre Albino, Catanduva, Brazil
30 Department of Surgery, Mazzoni Hospital, Ascoli Piceno, Italy
31 Department of Surgery, Mellini Hospital, Chiari (BS), Italy
32 Department of General and Digestive Surgery, Virgen de la Victoria, University Hospital, Malaga, Spain
33 Department of General Surgery and Surgical Oncology, Université de Nice Sophia-Antipolis, Universitary Hospital of Nice, Nice, France
34 Department of Surgery, Hospital and Oncological Centre, Novy Jicin, Czech Republic
35 Department of General Surgery, Lviv Emergency Hospital, Lviv, Ukraine
36 Department of Surgery, University Hospital Center Zagreb, Zagreb, Croatia
37 3rd Department of General Surger Jagiellonian Univeristy, Narutowicz Hospital, Krakow, Poland
38 Department of Surgery, Mozyr City Hospital, Mozyr, Belarus
39 Department of Surgery, Ancona University, Ancona, Italy
40 Department of Surgery, Ripas Hospital, Bandar Seri Begawan, Brunei
41 Clinical Sciences, Regional Hospitals Limbe and Buea, Limbe, Cameroon
42 Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
43 Division of Trauma and Surgical Critical Care, Department of Surgery, University of Ulsan, Seoul, Republic of Korea
44 II Cátedra de Clínica Quirúrgica, Hospital de Clínicas, Asuncion, Paraguay
45 Department of Surgery, Khamis Mushayt General Hospital, Khamis Mushayt, Saudi Arabia
46 Department of Surgery, Cutral Co Clinic, Neuquen, Argentina
47 Department of Surgery, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand
48 Department of Surgery, Thammasat University Hospital, Pathumthani, Thailand
49 Department of Surgery, Hospital Regional de Alta Especialidad del Bajio, Leon, Mexico
50 Department of Clinical and Experimental Sciences, Brescia University, Brescia, Italy
51 General Surgery, Adana Numune Training and Research Hospital, Adana, Turkey
52 Visceral Surgery, Military Hospital Desgenettes, Lyon, France
53 Visceral Surgery, Teaching Hospital Yalgado Ouedraogo, Ouagadougou, Burkina Faso
54 Department of Acute and Critical care medicine, Tokyo Medical and Dental University, Tokyo, Japan
55 The Shock Trauma and Emergency Medical Center, Matsudo City Hospital, Chiba, Japan
56 Emergency and Critical Care Center of Nippon Medical School, Tama-Nagayama Hospital, Tokyo, Japan
57 Department of Surgery, Our Lady of Lourdes Hospital, Drogheda, Ireland
58 Department of Surgery, Port Shepstone Hospital, Port Shepstone, South Africa
59 Department of Surgery, College of Health Sciences, Obafemi Awolowo University Hospital, Ile-Ife, Nigeria
60 Department of Emergency and Critical Care Medicine, Chiba University Hospital, Chiba, Japan
61 Department of Surgery, Bahrain Defence Force Hospital, Manama, Bahrain
62 Department of Emergency Medicine, Kyoto Second Red Cross Hospital, Kyoto, Japan
World Journal of Emergency Surgery 2013, 8:1 doi:10.1186/1749-7922-8-1
Published: 3 January 2013Abstract
Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18–98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.
The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.
