|
Etiology of Portal Vein Thrombosis (modified from Sobhonslidsuk A.) [4] |
|
| Thrombophilic Disorders |
Local factors |
|
|
|
| Inherited disorders |
Infections/inflammation |
| High risk of thrombosis (low prevalence): |
Neonatal omphalitis |
| Antithrombin III deficit |
Appendicitis |
| Protein C deficit |
Diverticulitis |
| Protein S deficit |
Pancreatitis |
| Cholecystitis |
|
| Low risk of thrombosis (high prevalence): |
Perforated peptic ulcer |
| Leiden V factor mutation |
Tuberculous lymphadenitis |
| Factor II mutation |
|
| Acquired disorders |
Portal vein injury |
| Malignancy |
Surgical shunts |
| Myeloproliferative disorders |
Splenectomy |
| Use of oral contraceptives |
Abdominal surgery |
| Antiphospholipid syndrome |
Liver transplants |
| Pregnancy and postpartum |
Blunt trauma |
| Paroxysmal nocturnal |
|
| hemoglobinuria |
|
| Mixed disorders |
Cancer of the abdominal organs Cirrhosis |
| Hyperhomocysteinemia |
|
Caronna et al. World Journal of Emergency Surgery 2008 3:24 doi:10.1186/1749-7922-3-24 |
|